Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158799 | 0.93 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTPOLBTSHR | |
| Hydrochloric Acid SCHEMBL5431696 | 0.91 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTPOLBTSHR | |
| SCHEMBL33574 | 0.88 | HTT (0.54) | ALDH1A1HTTMAPTPOLBTSHR | |
| Hydrochloric Acid SCHEMBL6742521 | 0.85 | HTT (0.52) | ALDH1A1HTTMAPTPOLBTSHR | |
| SCHEMBL5219140 | 0.84 | ALDH1A1 (0.50) | ALDH1A1HTTMAPTPOLBTSHR | |
| SCHEMBL33589 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MAPTPOLBTSHRTP53 | |
| SCHEMBL12964261 | 0.79 | NOS3 (0.42) | ALDH1A1HTTMAPTPOLBTSHR | |
| SCHEMBL3946139 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HTTMAPTPOLBTSHR | |
| SCHEMBL20012880 | 0.77 | NOS3 (0.41) | ALDH1A1HTTMAPTPOLBTSHR | |
| Hydrochloric Acid SCHEMBL7931830 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTPOLBTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5203875-A | Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance | L'OREAL (FR) | 1993-04-20 | — | — | US | claimed |
| EP-2473152-B1 | COMPOSITION COMPRISING A HYDROPHOBIC DYE, A SPECIFIC MINERAL AND/OR ORGANIC ALKALINE AGENT, A SPECIFIC COMPOUND (I) AND A SPECIFIC ORGANIC COMPOUND (II), AND USE THEREOF IN DYEING | OREAL (FR) | 2020-03-18 | — | — | EP | disclosed |
| US-20020078512-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibres | L'OREAL S.A. | 2002-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020078512-A1 | Oxidizing composition and uses for dyeing, for permanently reshaping or for bleaching keratin fibres | KRT18, ALDH1A2, ALDH1A3 | ALDH1A1 161/4885HTT 2282/4885MAPT 1533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.