Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663791 | 0.87 | MMP2 (0.46) | MMP2ALDH1A1MAPTSMN1; SMN2GLA | |
| SCHEMBL10448234 | 0.87 | MMP2 (0.46) | MMP2ALDH1A1MAPTSMN1; SMN2GLA | |
| SCHEMBL6771642 | 0.87 | LTA4H (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAHTT | |
| Hydrochloric Acid SCHEMBL4083238 | 0.86 | MMP2 (0.45) | MMP2ALDH1A1MAPTSMN1; SMN2GLA | |
| Hydrochloric Acid SCHEMBL5498773 | 0.86 | MMP2 (0.45) | MMP2ALDH1A1MAPTSMN1; SMN2GLA | |
| Hydrochloric Acid SCHEMBL1821105 | 0.86 | MMP2 (0.45) | MMP2ALDH1A1MAPTSMN1; SMN2GLA | |
| SCHEMBL10961448 | 0.86 | PDF (0.50) | ALDH1A1MAPTSMN1; SMN2GLALMNA | |
| Acetic Acid SCHEMBL11421148 | 0.83 | ALDH1A1 (0.46) | MMP2ALDH1A1MAPTSMN1; SMN2GLA | |
| SCHEMBL16446037 | 0.80 | PDF (0.50) | MMP2ALDH1A1MAPTSMN1; SMN2GLA | |
| SCHEMBL30999020 | 0.79 | ALDH1A1 (0.44) | MMP2ALDH1A1MAPTSMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156129-A1 | Method of treating pruritus and a pharmaceutical composition for the method | IKEDA MOHANDO CO., LTD. (JP) | 2002-10-24 | — | — | US | claimed |
| US-20020156129-A1 | Method of treating pruritus and a pharmaceutical composition for the method | IKEDA MOHANDO CO., LTD. (JP) | 2002-10-24 | — | — | US | disclosed |