Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311247 | 0.83 | ADORA2A (0.38) | KDM4EALDH1A1HSD17B10IKBKBNOTUM | |
| SCHEMBL5315316 | 0.80 | NOTUM (0.41) | HSD17B10NPSR1NOTUMNPC1RAB9A | |
| SCHEMBL5310750 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1NOTUMSMN1; SMN2 | |
| SCHEMBL8148454 | 0.76 | RXRA (0.51) | KDM4EGAAACHELMNAL3MBTL1 | |
| SCHEMBL27850006 | 0.76 | KDM4E (0.38) | KDM4EALDH1A1HSD17B10NPSR1XBP1 | |
| SCHEMBL8138706 | 0.73 | PTGS2 (0.53) | HDAC4HDAC6 | |
| SCHEMBL7602471 | 0.71 | NPC1 (0.46) | KDM4EALDH1A1NPSR1NPC1RAB9A | |
| SCHEMBL7601915 | 0.70 | STAT3 (0.41) | KDM4EHDAC4HDAC6MEN1KMT2A | |
| SCHEMBL15578377 | 0.70 | KIF11 (0.40) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL21339924 | 0.68 | HDAC6 (0.44) | IKBKBNPC1RAB9ATDO2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816347-B1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | BASF AG (DE) | 2007-06-20 | — | — | EP | claimed |
| US-5945538-A | Ammonium oxazole and amino oxazolium intermediates, methods for the preparation thereof and the use therefor in the manufacture of insecticidal arylpyrroles | AMERICAN CYANAMID COMPANY (US) | 1999-08-31 | — | — | US | claimed |
| EP-0816347-A1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | American Cyanamid Company (US) | 1998-01-07 | — | — | EP | claimed |
| EP-0816347-B1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | BASF AG (DE) | 2007-06-20 | — | — | EP | disclosed |
| US-5945538-A | Ammonium oxazole and amino oxazolium intermediates, methods for the preparation thereof and the use therefor in the manufacture of insecticidal arylpyrroles | AMERICAN CYANAMID COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| US-5925773-A | Ammonium oxazole and amino oxazolium intermediates, methods for the preparation thereof and the use thereof in the manufacture of insecticidal arylpyrroles | AMERICAN CYANAMID COMPANY (US) | 1999-07-20 | — | — | US | disclosed |
| EP-0816347-A1 | Ammonium oxazole- and amino oxazolium intermediates, methods for their preparation and their use in the manufacture of insecticidal, acaricidal and nematocidal arylpyrrole derivatives | American Cyanamid Company (US) | 1998-01-07 | — | — | EP | disclosed |