Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1452608 | 0.85 | HTR6 (0.41) | KDM4EHTR2ACYP2D6LMNATP53 | |
| Lithium SCHEMBL5702700 | 0.83 | HTR6 (0.40) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL5702695 | 0.83 | HTR6 (0.40) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL7997221 | 0.81 | SIGMAR1 (0.30) | GPR3SIGMAR1 | |
| SCHEMBL1454246 | 0.79 | — | — | |
| SCHEMBL1030004 | 0.77 | HTR2A (0.38) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL5837267 | 0.77 | GPR3 (0.46) | GPR3HTR2ACYP2D6CHRM2CHRM1 | |
| SCHEMBL9144758 | 0.76 | HTR2A (0.36) | KDM4EHTR2ACYP2D6LMNATP53 | |
| Lithium SCHEMBL9145158 | 0.76 | HTR2A (0.36) | KDM4EHTR2ACYP2D6LMNATP53 | |
| SCHEMBL9144761 | 0.76 | HTR2A (0.36) | KDM4EHTR2ACYP2D6LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015463-B1 | METHOD FOR PRODUCING METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2002-12-11 | — | — | EP | disclosed |
| CN-1275985-A | Bridged fluorenyl/indenyl metallocenes and their use | PHILLIPS PETROLEUM CO (US) | 2000-12-06 | — | — | CN | disclosed |
| EP-1023298-A1 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | Phillips Petroleum Company (US) | 2000-08-02 | — | — | EP | disclosed |
| EP-1023298-A4 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | PHILLIPS PETROLEUM CO (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999014219-A1 | BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF | PHILLIPS PETROLEUM COMPANY (US) | 1999-03-25 | — | — | WO | disclosed |
| US-5886202-A | HAVING UNUSUAL EFFECTIVENESS AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS WHEN CERTAIN SUBSTITUENTS ARE AT THE 3 POSITION OF THE INDENE; HIGHER-MOLECULAR-WEIGHT POLYOLEFINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 1999-03-23 | — | — | US | disclosed |