SCHEMBL7997221

SCHEMBL7997221

CC(c1ccccc1)(C1C=Cc2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.30
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8142258 0.87 SIGMAR1 (0.34) SIGMAR1
SCHEMBL7602505 0.81 GPR3 (0.33) SIGMAR1GPR3
SCHEMBL8971340 0.79 TSHR (0.31)
SCHEMBL12815944 0.77 SIGMAR1 (0.34) SIGMAR1
SCHEMBL12816183 0.74 ALDH1A1 (0.33) SIGMAR1
SCHEMBL1539718 0.73 HTR2A (0.35) SIGMAR1
SCHEMBL12814844 0.73 HTR2A (0.35) SIGMAR1
SCHEMBL1452608 0.73 HTR6 (0.41) SIGMAR1
SCHEMBL1030004 0.73 HTR2A (0.38) SIGMAR1
SCHEMBL12815279 0.73 GPR3 (0.40) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023298-A1 BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF Phillips Petroleum Company (US) 2000-08-02 EP disclosed
EP-1023298-A4 BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF PHILLIPS PETROLEUM CO (US) 2000-08-02 EP disclosed
WO-1999014219-A1 BRIDGE FLUORENYL/INDENYL METALLOCENES AND THE USE THEREOF PHILLIPS PETROLEUM COMPANY (US) 1999-03-25 WO disclosed
US-5886202-A HAVING UNUSUAL EFFECTIVENESS AS CATALYSTS FOR THE POLYMERIZATION OF OLEFINS WHEN CERTAIN SUBSTITUENTS ARE AT THE 3 POSITION OF THE INDENE; HIGHER-MOLECULAR-WEIGHT POLYOLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP 1999-03-23 US disclosed