Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048648 | 0.99 | TSHR (0.40) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL22423614 | 0.90 | TSHR (0.39) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL17483208 | 0.86 | HDAC8 (0.36) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL881201 | 0.85 | ALDH1A1 (0.35) | ALDH1A1GAAAPEX1FABP4MAPK1 | |
| SCHEMBL1714142 | 0.84 | HDAC3 (0.40) | ALDH1A1APEX1MAPK1 | |
| SCHEMBL13264906 | 0.84 | CYP26B1 (0.35) | ALDH1A1GAAAPEX1TDP1FABP4 | |
| SCHEMBL10037947 | 0.84 | TSHR (0.36) | ALDH1A1KDM4ELMNATSHRKMT2A | |
| SCHEMBL24934384 | 0.83 | ALDH1A1 (0.41) | ALDH1A1LTB4R | |
| SCHEMBL2721464 | 0.83 | P2RX3 (0.35) | ALDH1A1GAAAPEX1TDP1FABP4 | |
| SCHEMBL14048649 | 0.83 | APEX1 (0.39) | ALDH1A1APEX1FABP4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9423323-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2016-08-23 | — | — | US | disclosed |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-09-03 | — | — | US | disclosed |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-9018396-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2015-04-28 | — | — | US | disclosed |
| US-8569506-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2013-10-29 | — | — | US | disclosed |
| US-8426618-B2 | Luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120288871-A1 | Modified Carbocyanine Dyes and Their Conjugates | Life Technologies Corporation (US) | 2012-11-15 | — | — | US | disclosed |
| US-8252932-B2 | Modified carbocyanine dyes and their conjugates | Life Technologies Corporation (US) | 2012-08-28 | — | — | US | disclosed |
| US-20120123109-A1 | Luminescence quenching compounds | ANASPEC INCORPORATED (US) | 2012-05-17 | — | — | US | disclosed |
| US-20110171678-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | Life Technologies Corporation (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171678-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | ALDH1A1 385/4885KDM4E 2829/4885LMNA 2822/4885 |
| US-20120288871-A1 | Modified Carbocyanine Dyes and Their Conjugates | IK, CBR3, DRD5 | ALDH1A1 385/4885KDM4E 2829/4885LMNA 2822/4885 |
| US-20120123109-A1 | Luminescence quenching compounds | ABCG2, TYR, GFPT1 | ALDH1A1 430/4885KDM4E 2017/4885LMNA 2631/4885 |
| US-20150218380-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | ALDH1A1 385/4885KDM4E 2829/4885LMNA 2822/4885 |
| US-20150247785-A1 | MODIFIED CARBOCYANINE DYES AND THEIR CONJUGATES | IK, CBR3, DRD5 | ALDH1A1 385/4885KDM4E 2829/4885LMNA 2822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.