Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048649 | 0.99 | APEX1 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL15304503 | 0.94 | APEX1 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3340797 | 0.94 | APEX1 (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7602622 | 0.84 | ALDH1A1 (0.40) | APEX1MAPK1ALDH1A1 | |
| SCHEMBL559121 | 0.83 | NPSR1 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1715045 | 0.83 | CASP3 (0.34) | NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL14048648 | 0.83 | TSHR (0.40) | APEX1ALDH1A1 | |
| SCHEMBL22423608 | 0.81 | F13A1 (0.33) | HDAC11NPSR1ALDH1A1 | |
| SCHEMBL24584317 | 0.81 | PTGS2 (0.38) | MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12012082 | 0.81 | TBXAS1 (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834489-B2 | Methods for quantifying ligand efficacy in G-protein coupled receptors using single-molecule fluorescence energy transfer | CORNELL UNIVERSITY (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230270890-A1 | FLUORESCENT COMPOUND FOR DETECTING BIOLOGICAL MATERIAL AND PREPARATION METHOD THEREOF | BIOACTS CORPORATION (KR) | 2023-08-31 | — | — | US | disclosed |
| US-20170313883-A1 | FLUORESCENCE COMPOUNDS AND PREPARATION METHOD THEREOF | BIOACTS CO., LTD. (KR) | 2017-11-02 | — | — | US | disclosed |
| US-8378120-B2 | Method and reagent for measuring nitroreductase enzyme activity | GE HEALTHCARE UK LIMITED (GB) | 2013-02-19 | — | — | US | disclosed |
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| EP-1525265-B1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2258776-A1 | Fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-2258776-A1 | Fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |
| US-7615646-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-10 | — | — | US | disclosed |
| CN-101522815-A | Unsymmetrical fluoro-substituted polymethine dyes | GE HEALTHCARE UK LTD (NO) | 2009-09-02 | — | — | CN | disclosed |
| US-7579140-B2 | Method and reagent for measuring nitroreductase enzyme activity | GE HEALTHCARE UK LIMITED (GB) | 2009-08-25 | — | — | US | disclosed |
| US-20080317674-A1 | Method and Reagent for Measuring Nitroreductase Enzyme Activity | GE HEALTHCARE UK LIMITED (GB) | 2008-12-25 | — | — | US | disclosed |
| EP-1749103-A1 | METHOD AND REAGENT FOR MEASURING NITROREDUCTASE ENZYME ACTIVITY | GE Healthcare UK Limited (GB) | 2007-02-07 | — | — | EP | disclosed |
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-03-09 | — | — | US | disclosed |
| WO-2005118839-A1 | METHOD AND REAGENT FOR MEASURING NITROREDUCTASE ENZYME ACTIVITY | GE HEALTHCARE UK LIMITED (GB) | 2005-12-15 | — | — | WO | disclosed |
| EP-1525265-A4 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1525265-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE-MELLON UNIVERSITY (US) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004039894-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | IDO1, TDO2, IDO2 | HDAC3 1285/4885HDAC4 3911/4885HDAC1 3278/4885 |
| US-11834489-B2 | Methods for quantifying ligand efficacy in G-protein coupled receptors using single-molecule fluorescence energy transfer | GPR3, GPR4, GPR68 | HDAC3 2953/4885HDAC4 3843/4885HDAC1 4529/4885 |
| US-20230270890-A1 | FLUORESCENT COMPOUND FOR DETECTING BIOLOGICAL MATERIAL AND PREPARATION METHOD THEREOF | F12, MRGPRX4, C3AR1 | HDAC3 1043/4885HDAC4 3107/4885HDAC1 1601/4885 |
| US-20170313883-A1 | FLUORESCENCE COMPOUNDS AND PREPARATION METHOD THEREOF | CDY1; CDY1B, CYP2F1, CYP4F11 | HDAC3 1155/4885HDAC4 3922/4885HDAC1 1681/4885 |
| US-20080317674-A1 | Method and Reagent for Measuring Nitroreductase Enzyme Activity | CBR3, CBR1, SQOR | HDAC3 1327/4885HDAC4 1884/4885HDAC1 1691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.