SCHEMBL7602677

SCHEMBL7602677

CCC1=C2c3c(-c4ccccc4)cccc3C1[Hf](C)(C)C1C(CC)=C(c3c(-c4ccccc4)cccc31)[Si]2(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL797728 0.85
SCHEMBL7602120 0.80 KDM4E (0.32)
SCHEMBL7599210 0.80
SCHEMBL7603055 0.78 HTR7 (0.37) EDNRBEDNRA
SCHEMBL7602016 0.77 HTR1A (0.33) EDNRBEDNRA
SCHEMBL797937 0.75
SCHEMBL7604203 0.75
SCHEMBL7603235 0.74
SCHEMBL7601517 0.72
SCHEMBL17387103 0.72 PDCD1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US claimed
US-6410665-B1 POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN BASELL POLYOLEFINE GMBH (DE) 2002-06-25 US disclosed