Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797306 | 0.84 | SOAT1 (0.30) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7603055 | 0.80 | HTR7 (0.37) | HTR1AHTR7BRD4EDNRBEDNRA | |
| SCHEMBL7598786 | 0.79 | HTR1A (0.30) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7602713 | 0.77 | HTR1A (0.37) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7602677 | 0.77 | EDNRB (0.31) | EDNRBEDNRA | |
| SCHEMBL797081 | 0.74 | SOAT1 (0.30) | — | |
| SCHEMBL7599191 | 0.69 | HTR1A (0.34) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL17387021 | 0.68 | HTR1A (0.30) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL5359571 | 0.68 | BRD4 (0.34) | BRD4 | |
| SCHEMBL7194429 | 0.68 | BRD4 (0.32) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |