Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.37 |
| ▸ | HTR1A | P08908 | 5/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797798 | 0.84 | HTR7 (0.36) | HTR7HTR1ADRD2CYP19A1CYP11B1 | |
| SCHEMBL7599331 | 0.82 | HTR1A (0.34) | HTR7HTR1ADRD2CYP11B2BRD4 | |
| SCHEMBL7607516 | 0.81 | HTR2A (0.33) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7602016 | 0.80 | HTR1A (0.33) | HTR7HTR1ABRD4EDNRBEDNRA | |
| SCHEMBL7598778 | 0.78 | BRD4 (0.33) | HTR7HTR1ADRD2CYP19A1CYP11B1 | |
| SCHEMBL7602677 | 0.78 | EDNRB (0.31) | EDNRBEDNRA | |
| SCHEMBL796599 | 0.74 | HTR1A (0.31) | HTR7HTR1ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL797677 | 0.72 | HTR1A (0.34) | HTR7HTR1ADRD2 | |
| SCHEMBL5359571 | 0.69 | BRD4 (0.34) | BRD4 | |
| SCHEMBL17387103 | 0.67 | PDCD1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |