Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797236 | 0.80 | SLC6A4 (0.35) | ALDH1A1MAPTKDM4ELMNASLC6A4 | |
| SCHEMBL5351880 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CYP2A6MAPTKDM4ELMNA | |
| SCHEMBL7602713 | 0.66 | HTR1A (0.37) | ALDH1A1MAPTKDM4ELMNASLC6A4 | |
| SCHEMBL3922333 | 0.66 | ALDH1A1 (0.36) | ALDH1A1CYP2A6MAPTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL2119949 | 0.65 | ALDH1A1 (0.35) | ALDH1A1CYP2A6MAPTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL1129509 | 0.65 | ALDH1A1 (0.35) | ALDH1A1CYP2A6MAPTKDM4ELMNA | |
| Hydrochloric Acid SCHEMBL6255103 | 0.65 | ALDH1A1 (0.35) | ALDH1A1CYP2A6MAPTKDM4ELMNA | |
| SCHEMBL12537735 | 0.61 | ALDH1A1 (0.43) | ALDH1A1CYP2A6MAPTKDM4ELMNA | |
| SCHEMBL10953803 | 0.60 | DHFR (0.42) | ALDH1A1CYP2A6MAPTKDM4ELMNA | |
| SCHEMBL12278879 | 0.60 | ALDH1A1 (0.46) | ALDH1A1CYP2A6MAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |