Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797176 | 0.84 | HTR1A (0.34) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7602120 | 0.75 | KDM4E (0.32) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL796360 | 0.74 | MEN1 (0.32) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7597692 | 0.69 | HTR7 (0.38) | HTR1AHTR7MAPTSLC6A4 | |
| SCHEMBL7603358 | 0.65 | MEN1 (0.38) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL797793 | 0.64 | MEN1 (0.33) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL797522 | 0.64 | MEN1 (0.35) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL7600122 | 0.61 | ALDH1A1 (0.33) | KDM4ELMNAALDH1A1MAPK1MAPT | |
| SCHEMBL7607532 | 0.60 | SLC6A4 (0.33) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL2539931 | 0.60 | CYP2A6 (0.48) | KDM4ELMNAALDH1A1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |