Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602118 | 0.87 | NPC1 (0.60) | NPC1RAB9AGABRA1GABRB2KDM4E | |
| SCHEMBL6012095 | 0.84 | RAB9A (0.59) | NPC1RAB9AGABRA1GABRB2KDM4E | |
| SCHEMBL4259535 | 0.83 | RAB9A (0.57) | NPC1RAB9AGABRA1GABRB2KDM4E | |
| SCHEMBL7011129 | 0.82 | ALDH1A1 (0.74) | NPC1RAB9AGABRA1GABRB2KDM4E | |
| SCHEMBL13069156 | 0.81 | NPC1 (0.53) | NPC1RAB9AGABRA1GABRB2KDM4E | |
| SCHEMBL7820531 | 0.77 | NPC1 (0.72) | NPC1RAB9AGABRA1GABRB2KDM4E | |
| SCHEMBL2929147 | 0.77 | GABRB2 (0.73) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL2935064 | 0.76 | GABRB2 (0.71) | GABRA1GABRB2KDM4EHPGDHSD17B10 | |
| SCHEMBL1761262 | 0.75 | RAB9A (0.49) | NPC1RAB9AGABRA1GABRB2KDM4E | |
| SCHEMBL8288559 | 0.74 | TP53 (0.59) | NPC1RAB9AGABRA1GABRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183377-B2 | Process for the preparation of imidazopyridines | ELDER PHARMACEUTICALS LTD. | 2012-05-22 | — | — | US | disclosed |
| US-8183377-B2 | Process for the preparation of imidazopyridines | ELDER PHARMACEUTICALS LTD. | 2012-05-22 | — | — | US | disclosed |
| EP-1917263-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD (IN) | 2010-11-24 | — | — | EP | disclosed |
| US-20100036129-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD. (IN) | 2010-02-11 | — | — | US | disclosed |
| US-20100036129-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | ELDER PHARMACEUTICALS LTD. (IN) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036129-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOPYRIDINES | OTC, ODC1, OGDH | NPC1 3053/4885RAB9A 2279/4885GABRA1 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.