Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL218124 | 0.82 | HTR7 (0.36) | HTR7HTR1ADHFRMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL218908 | 0.82 | HTR7 (0.36) | HTR7HTR1ADHFRMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL5616525 | 0.81 | DHFR (0.35) | DHFRMTNR1AMTNR1BSLC6A2SLC6A4 | |
| SCHEMBL7602061 | 0.80 | HTR7 (0.39) | HTR7HTR1ADHFRMTNR1AMTNR1B | |
| SCHEMBL7602791 | 0.80 | HTR7 (0.36) | HTR7HTR1ADHFRMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL216589 | 0.74 | HTR7 (0.34) | HTR7HTR1ADHFRMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL219041 | 0.74 | HTR7 (0.34) | HTR7HTR1ADHFRMTNR1AMTNR1B | |
| SCHEMBL796777 | 0.73 | HTR7 (0.36) | HTR7HTR1ADHFRCNR1CNR2 | |
| SCHEMBL796673 | 0.73 | HTR7 (0.36) | HTR7HTR1AMTNR1AMTNR1BCNR1 | |
| Hydrochloric Acid SCHEMBL8158808 | 0.72 | HTR1A (0.35) | HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007023618-A1 | HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-01 | — | — | WO | disclosed |