Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HNF4A | P41235 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 3/20 | 0.30 |
| ▸ | EDNRA | P25101 | 3/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5616436 | 0.80 | ALDH1A1 (0.31) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5616232 | 0.78 | HTR1A (0.34) | PDCD1CD274HTR2BTMEM97HTR1A | |
| SCHEMBL7599191 | 0.77 | HTR1A (0.34) | PDCD1CD274HTR2BTMEM97HTR1A | |
| SCHEMBL7602972 | 0.77 | PDCD1 (0.34) | PDCD1CD274HTR2BTMEM97HTR1A | |
| Hydrochloric Acid SCHEMBL1775471 | 0.77 | PDCD1 (0.31) | PDCD1CD274HNF4AEDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL5616377 | 0.73 | BRD4 (0.31) | BRD4 | |
| SCHEMBL797644 | 0.70 | GCGR (0.34) | PDCD1CD274 | |
| SCHEMBL797526 | 0.70 | GCGR (0.34) | PDCD1CD274HTR2BTMEM97HTR1A | |
| Hydrochloric Acid SCHEMBL6047511 | 0.66 | HTR1A (0.31) | HTR2BTMEM97HTR1AHTR7SIGMAR1 | |
| SCHEMBL7602016 | 0.66 | HTR1A (0.33) | HTR2BTMEM97HTR1AHTR7SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007023618-A1 | HOMOPOLYMER AND COPOLYMER, AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-03-01 | — | — | WO | disclosed |