SCHEMBL7602983

SCHEMBL7602983

CCC(=O)N(O)c1ccccc1C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
CYP3A4 P08684 2/20 0.46
TRPM8 Q7Z2W7 1/20 0.46
ALDH1A1 P00352 3/20 0.45
TP53 P04637 1/20 0.45
KDM4E B2RXH2 2/20 0.44
OPRM1 P35372 1/20 0.43
TSHR P16473 3/20 0.41
NPSR1 Q6W5P4 1/20 0.40
TEAD1 P28347 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23031991 0.82 LMNA (0.49) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL4781144 0.81 CYP3A4 (0.46) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL7867200 0.79 CYP3A4 (0.61) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL6638391 0.78 LMNA (0.47) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL8187602 0.78 TRPM8 (0.50) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL3285068 0.78 LMNA (0.51) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL7601412 0.77 ALDH1A1 (0.44) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL11224647 0.77 ALDH1A1 (0.46) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL9175691 0.77 ALDH1A1 (0.44) LMNACYP3A4TRPM8ALDH1A1TP53
SCHEMBL8922646 0.75 TRPM8 (0.53) LMNACYP3A4TRPM8ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0624155-B2 CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM BASF AG (DE) 2002-12-11 EP disclosed
US-6075148-A CARBAMATE DERIVATIVES ARE USEFUL FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES BASF AKTIENGESELLSCHAFT (DE) 2000-06-13 US disclosed
US-5981532-A FOR CONTROLLING FUNGI, INSECTS, NEMATODES AND SPIDER MITES BASF AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed
US-5824705-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-20 US disclosed
EP-0624155-B1 CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM BASF AG (DE) 1998-05-06 EP disclosed
EP-0624155-A1 CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM BASF Aktiengesellschaft (DE) 1994-11-17 EP disclosed
WO-1993015046-A1 CARBAMATES AND PLANT-PROTECTING AGENTS CONTAINING THEM BASF AKTIENGESELLSCHAFT (DE) 1993-08-05 WO disclosed