Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137486 | 0.89 | TDP1 (0.83) | TDP1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL28286830 | 0.87 | TDP1 (0.79) | TDP1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL16217656 | 0.87 | TDP1 (0.79) | TDP1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL547137 | 0.87 | TDP1 (0.79) | TDP1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL13292516 | 0.87 | TDP1 (0.79) | TDP1LMNANPC1RAB9AALDH1A1 | |
| Ethylene SCHEMBL8622525 | 0.85 | TDP1 (0.76) | TDP1LMNANPC1RAB9AALDH1A1 | |
| Ethylene SCHEMBL11578922 | 0.85 | TDP1 (0.76) | TDP1LMNANPC1RAB9AALDH1A1 | |
| Ethylene SCHEMBL9928862 | 0.85 | TDP1 (0.76) | TDP1LMNANPC1RAB9AALDH1A1 | |
| Ethylene SCHEMBL7587624 | 0.85 | TDP1 (0.76) | TDP1LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL7935103 | 0.84 | TDP1 (0.57) | TDP1LMNANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464232-B2 | Compound, liquid crystal composition, polymer material, and film | FUJIFILM CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20140339470-A1 | COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL, AND FILM | FUJIFILM CORPORATION (JP) | 2014-11-20 | — | — | US | disclosed |
| EP-1266900-A1 | Carbamates of rapamycin | Wyeth (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0593227-A1 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5302584-A | Immunosuppressants | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140339470-A1 | COMPOUND, LIQUID CRYSTAL COMPOSITION, POLYMER MATERIAL, AND FILM | CCL11, AQP1, FANCF | TDP1 2891/4885LMNA 1134/4885NPC1 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.