Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875175 | 0.89 | TDP1 (0.68) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL51601 | 0.89 | TDP1 (0.68) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL7603210 | 0.84 | TDP1 (0.68) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| Ethylene Glycol SCHEMBL15661698 | 0.83 | ALDH1A1 (0.62) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL9817384 | 0.82 | TDP1 (0.59) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL15424736 | 0.82 | ALDH1A1 (0.60) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL4570317 | 0.82 | TDP1 (0.59) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL21953404 | 0.81 | TDP1 (0.67) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL5210552 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL7371028 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102272117-A | Benzothiopyran derivatives as HIF hydroxylase inhibitors | — | 2011-12-07 | — | — | CN | disclosed |
| WO-2009149436-A1 | SUBSTITUTED AMINOTHIAZOLE PRODRUGS OF COMPOUNDS WITH ANTI-HCV ACTIVITY | ACHILLION PHARMACEUTICALS, INC. (US) | 2009-12-10 | — | — | WO | disclosed |
| US-6242600-B1 | ANTIISCHEMIC AGENTS, ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |