Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MYB | P10242 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7602562 | 0.82 | HTR1A (0.34) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL7602972 | 0.75 | PDCD1 (0.34) | ALDH1A1HSD17B10HTR1AHTR7HTR2B | |
| SCHEMBL7601455 | 0.73 | DHFR (0.32) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL5355719 | 0.72 | ALDH1A1 (0.33) | MAPTKDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL796360 | 0.71 | MEN1 (0.32) | MEN1KMT2AKDM4ELMNATDP1 | |
| SCHEMBL7597779 | 0.71 | IDO1 (0.33) | MEN1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL797793 | 0.70 | MEN1 (0.33) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL7599708 | 0.65 | KDM4E (0.31) | MAPTKDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL2539931 | 0.62 | CYP2A6 (0.48) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL12537735 | 0.60 | ALDH1A1 (0.43) | MEN1KMT2AMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | claimed |
| US-6410665-B1 | POLYMERIZATION COORDINATION CATALYST FOR ALPHA-OLEFIN | BASELL POLYOLEFINE GMBH (DE) | 2002-06-25 | — | — | US | disclosed |