Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 16/20 | 0.43 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598808 | 0.96 | ESR1 (0.43) | ESR1F12ESR2MEN1KMT2A | |
| SCHEMBL9043472 | 0.86 | SLC6A3 (0.41) | ESR1CASP3SENP7 | |
| SCHEMBL8860947 | 0.86 | SLC6A3 (0.41) | ESR1CASP3SENP7 | |
| SCHEMBL8749295 | 0.85 | KDM4E (0.44) | ESR1MEN1KMT2ACASP3SENP7 | |
| SCHEMBL8854606 | 0.84 | ESR1 (0.52) | ESR1 | |
| SCHEMBL7598473 | 0.82 | KDM4E (0.46) | ESR1 | |
| SCHEMBL8058782 | 0.81 | FAAH (0.43) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL734321 | 0.81 | FAAH (0.43) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL8749311 | 0.80 | EPHX2 (0.39) | ESR1MEN1KMT2A | |
| SCHEMBL8749366 | 0.78 | ESR1 (0.35) | ESR1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417380-B1 | POLYCYCLOALKYL KETONE CONTAINING FLUORESCENT CHROMOPHORE IS ALKYLATED TO POLYCYCLOALKYLIDENE ETHER IN PRESENCE OF ALKALI METAL ALKOXIDE IN POLAR APROTIC SOLVENT | APPLIED BIOSYSTEMS, LLC | 2002-07-09 | — | — | US | disclosed |
| US-6124478-A | Methods of using 1,2-dioxetanes and kits therefore | TROPIX, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0582317-B1 | Synthesis of 1,2-dioxetanes and intermediates therefor | TROPIX INC (US) | 1999-08-25 | — | — | EP | disclosed |
| US-5648555-A | Alkenes | APPLIED BIOSYSTEMS, LLC | 1997-07-15 | — | — | US | disclosed |
| US-5639907-A | Synthesis of 1,2-dioxetanes and intermediates therefor | TROPIX, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| US-5637747-A | Synthesis of 1,2-dioxetanes and intermediates therefor | TROPIX, INC. (US) | 1997-06-10 | — | — | US | disclosed |
| US-5625077-A | 1,2-dioxetanes | TROPIX, INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0368946-B1 | 1,2-DIOXETANES | TROPIX INC (US) | 1994-09-14 | — | — | EP | disclosed |
| US-5177241-A | SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | APPLIED BIOSYSTEMS, LLC | 1993-01-05 | — | — | US | disclosed |
| US-4956477-A | Synthesis of 1,2-dioxetanes | TROPIX, INC. (US) | 1990-09-11 | — | — | US | disclosed |
| EP-0368946-A1 | 1,2-DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0368946-A4 | 1,2-DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-05-14 | — | — | EP | disclosed |
| WO-1989006226-A1 | SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | QUEST SYSTEMS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |