Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.31 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603365 | 0.89 | GPR84 (0.38) | ESR1NPC1RAB9AHPGDSCNR2 | |
| SCHEMBL8749295 | 0.84 | KDM4E (0.44) | ESR1NPC1RAB9AHPGDSCNR2 | |
| SCHEMBL7598473 | 0.81 | KDM4E (0.46) | ESR1NPC1RAB9AHPGDSCNR2 | |
| SCHEMBL8749311 | 0.81 | EPHX2 (0.39) | ESR1NPC1RAB9AKDM4EKDM2B | |
| SCHEMBL8860947 | 0.80 | SLC6A3 (0.41) | ESR1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL9043472 | 0.80 | SLC6A3 (0.41) | ESR1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL7602742 | 0.79 | EPHX2 (0.41) | ESR1NPC1RAB9AKDM4EKDM2B | |
| SCHEMBL7603629 | 0.78 | ESR1 (0.43) | ESR1CASP3SENP7 | |
| SCHEMBL7603675 | 0.77 | ESR1 (0.33) | ESR1NPC1RAB9AKDM4EKDM2B | |
| SCHEMBL7598808 | 0.76 | ESR1 (0.43) | ESR1NPC1RAB9ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416038-B1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX INC (US) | 1997-03-26 | — | — | EP | disclosed |
| US-4952707-A | DECOMPOSITION TO LIGHT EMITTING FLUOROPHORE; ANALYSIS | TROPIX, INC. (US) | 1990-08-28 | — | — | US | disclosed |