Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043472 | 1.00 | SLC6A3 (0.41) | SLC6A3SLC6A4NPC1RAB9ACASP3 | |
| SCHEMBL7598473 | 0.87 | KDM4E (0.46) | SLC6A3SLC6A4NPC1RAB9APLAU | |
| SCHEMBL7598808 | 0.87 | ESR1 (0.43) | SLC6A3SLC6A4NPC1RAB9AESR1 | |
| SCHEMBL7603629 | 0.86 | ESR1 (0.43) | CASP3SENP7ESR1 | |
| SCHEMBL9616262 | 0.82 | PLAU (0.38) | PLAUESR1 | |
| SCHEMBL8749248 | 0.81 | KDM2B (0.41) | ESR1 | |
| SCHEMBL7602742 | 0.81 | EPHX2 (0.41) | SLC6A3NPC1RAB9AESR1 | |
| SCHEMBL734321 | 0.81 | FAAH (0.43) | NPC1RAB9AESR1 | |
| SCHEMBL8058782 | 0.81 | FAAH (0.43) | NPC1RAB9AESR1 | |
| SCHEMBL7603365 | 0.80 | GPR84 (0.38) | SLC6A3SLC6A4NPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9040665-A | — | — | None | — | — | JP | disclosed |
| JP-H0940665-A | ALKENE COMPOUND FOR PRODUCTION OF 1,2-DIOXETANE | TROPIX INC | 1997-02-10 | — | — | JP | disclosed |