Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186021 | 0.83 | ALDH1A1 (0.50) | L3MBTL1KDM4EHSD17B10CASP1ALOX5 | |
| SCHEMBL4687124 | 0.83 | BRD4 (0.40) | KDM4EHSD17B10CASP1BRD4LMNA | |
| SCHEMBL6639870 | 0.81 | KDM4E (0.50) | L3MBTL1KDM4EHSD17B10LMNANPC1 | |
| SCHEMBL9390418 | 0.79 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10754548 | 0.79 | ALOX5 (0.39) | L3MBTL1KDM4EHSD17B10CASP1ALOX5 | |
| SCHEMBL8516383 | 0.79 | TSHR (0.52) | L3MBTL1KDM4EHSD17B10ALOX5LMNA | |
| SCHEMBL7307854 | 0.77 | ALDH1A1 (0.53) | L3MBTL1KDM4EHSD17B10BRD4LMNA | |
| SCHEMBL10587030 | 0.77 | KDM4E (0.48) | L3MBTL1KDM4EHSD17B10CASP1ALOX5 | |
| SCHEMBL10511469 | 0.75 | ALDH1A1 (0.46) | KDM4EHSD17B10CASP1ALOX5BRD4 | |
| SCHEMBL6641775 | 0.75 | USP2 (0.45) | KDM4EHSD17B10LMNANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999020606-A2 | PIPERIDINES AND PIPERAZINES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1999-04-29 | — | — | WO | disclosed |
| WO-1998046599-A1 | NOVEL CARBOXAMIDES AS PLATELET AGGREGATION INHIBITORS | J. URIACH & CIA. S.A. (ES) | 1998-10-22 | — | — | WO | disclosed |
| EP-0371499-A2 | Process for the preparation of pyridine-2,3-dicarboxylic-acid esters | WACKER-CHEMIE GMBH (DE) | 1990-06-06 | — | — | EP | disclosed |
| EP-0298029-A1 | Substituted imidazolones with a herbicidal activity | CIBA-GEIGY AG (CH) | 1989-01-04 | — | — | EP | disclosed |