Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603908 | 0.83 | L3MBTL1 (0.43) | BRD4TYMSLMNAKDM4EHSD17B10 | |
| SCHEMBL11310549 | 0.79 | S1PR4 (0.35) | LMNAKDM4ES1PR4KMT2AGRM4 | |
| SCHEMBL2659030 | 0.78 | KDM4E (0.50) | BRD4LMNAKDM4EHSD17B10CYP1A2 | |
| SCHEMBL6186021 | 0.78 | ALDH1A1 (0.50) | BRD4LMNAKDM4EHSD17B10CYP1A2 | |
| SCHEMBL8516383 | 0.77 | TSHR (0.52) | TYMSLMNAKDM4EHSD17B10MAPT | |
| SCHEMBL3790540 | 0.76 | S1PR4 (0.50) | LMNAKDM4EMAPTALDH1A1S1PR4 | |
| SCHEMBL10587030 | 0.76 | KDM4E (0.48) | LMNAKDM4EHSD17B10CYP1A2CASP1 | |
| SCHEMBL7307854 | 0.76 | ALDH1A1 (0.53) | BRD4LMNAKDM4EHSD17B10CYP1A2 | |
| SCHEMBL5309545 | 0.75 | TRIM24 (0.40) | LMNAKDM4EMAPTS1PR4HTT | |
| SCHEMBL2828660 | 0.75 | S1PR4 (0.43) | LMNAKDM4ECYP3A4S1PR4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073638-B1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | ABBOTT GMBH & CO KG (DE) | 2008-07-23 | — | — | EP | disclosed |
| EP-1073638-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054304-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, THEIR PRODUCTION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-28 | — | — | WO | disclosed |