Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PPIA | P62937 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6612663 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL7603908 | 0.77 | L3MBTL1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL4687124 | 0.76 | BRD4 (0.40) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL8516383 | 0.72 | TSHR (0.52) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4771680 | 0.71 | KDM4E (0.71) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL6442879 | 0.71 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL8826118 | 0.71 | KDM4E (0.75) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10587030 | 0.70 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL6605329 | 0.70 | HTT (0.60) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL22731793 | 0.70 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630896-A1 | Substituted mono- and bipyridylmethyl derivatives as angiotensin II antagonist | BAYER AG (DE) | 1994-12-28 | — | — | EP | disclosed |