Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636347 | 0.87 | MAPT (0.45) | KMT2AMAPTMEN1MAOAMAOB | |
| SCHEMBL131516 | 0.81 | CYP19A1 (0.52) | MAPTMAOBHSD17B10CYP3A4ALDH1A1 | |
| SCHEMBL28691171 | 0.81 | HTR6 (0.39) | MAOAMAOBGRM5HIF1AALDH1A1 | |
| SCHEMBL2399209 | 0.79 | CA2 (0.45) | KMT2AMAPTMEN1TDP1CA12 | |
| SCHEMBL13730471 | 0.77 | CYP19A1 (0.49) | KMT2AMAPTMEN1MAOAMAOB | |
| SCHEMBL130268 | 0.77 | CYP19A1 (0.49) | KMT2AMAPTMEN1MAOAMAOB | |
| SCHEMBL28912178 | 0.76 | CA2 (0.43) | KMT2AMAPTMEN1TDP1CA12 | |
| SCHEMBL6703209 | 0.74 | CYP19A1 (0.42) | KMT2ATDP1ALDH1A1 | |
| SCHEMBL10360964 | 0.74 | MAOB (0.49) | MAOBALDH1A1 | |
| SCHEMBL19746 | 0.73 | CYP19A1 (0.45) | KMT2AMAPTMAOAMAOBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413998-B1 | BONE REGENERATION | OSTEOSCREEN, INC. | 2002-07-02 | — | — | US | disclosed |
| US-6008208-A | Compositions and methods for treating bone deficit conditions | OSTEOSCREEN, INC. (US) | 1999-12-28 | — | — | US | disclosed |