Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5359299 | 0.80 | HTR7 (0.36) | ALDH1A1TSHRGPR3HTR2A | |
| Hydrochloric Acid SCHEMBL5347487 | 0.80 | MYC (0.37) | ALDH1A1TSHRGPR3HTR2A | |
| Methane SCHEMBL6557709 | 0.79 | HTR7 (0.35) | ALDH1A1TSHRGPR3HTR2A | |
| Fluoride Ion SCHEMBL1131213 | 0.76 | HTR7 (0.36) | ALDH1A1TSHRGPR3HTR2A | |
| Hydrochloric Acid SCHEMBL7604666 | 0.74 | HTR2A (0.41) | NPC1ALDH1A1CYP3A4TSHRMAPK1 | |
| Ethane SCHEMBL8163438 | 0.72 | GPR3 (0.44) | TSHRGPR3HTR2A | |
| SCHEMBL7607095 | 0.71 | HTR2A (0.42) | NPC1ALDH1A1CYP3A4TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL618216 | 0.71 | GPR3 (0.42) | TSHRGPR3HTR2A | |
| Hydrochloric Acid SCHEMBL29912111 | 0.69 | GPR3 (0.34) | GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL30338176 | 0.69 | GPR3 (0.34) | GPR3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524624-B1 | Use of organometallic flurorenyl compounds. | PHILLIPS PETROLEUM CO (US) | 2002-05-15 | — | — | EP | disclosed |
| EP-0524624-A2 | Organometallic fluorenyl compounds, preparation, and use | PHILLIPS PETROLEUM COMPANY (US) | 1993-01-27 | — | — | EP | disclosed |