Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.78 |
| ▸ | KDM1A | O60341 | 4/20 | 0.78 |
| ▸ | EP300 | Q09472 | 4/20 | 0.78 |
| ▸ | ACHE | P22303 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | RAD52 | P43351 | 3/20 | 0.78 |
| ▸ | BCHE | P06276 | 3/20 | 0.78 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.78 |
| ▸ | DRD2 | P14416 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.78 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.78 |
| ▸ | RXRA | P19793 | 2/20 | 0.78 |
| ▸ | DRD1 | P21728 | 2/20 | 0.78 |
| ▸ | HTR2B | P41595 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29595926 | 0.88 | KDM1A (0.85) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL15669190 | 0.88 | ACHE (1.00) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL25632 | 0.88 | ACHE (1.00) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL29354144 | 0.88 | ACHE (1.00) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL30153843 | 0.88 | ACHE (1.00) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL2538316 | 0.87 | ACHE (0.98) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL3686644 | 0.87 | ACHE (0.98) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL21462194 | 0.87 | ACHE (0.98) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL153906 | 0.87 | ACHE (1.00) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A | |
| Berberine SCHEMBL4894622 | 0.87 | BCHE (0.98) | CYP3A4LMNAMAPTSMN1; SMN2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265485-A1 | USE OF PIPERIDINE BENZODERIVATIVES AS FUNGICIDES | Leis, Michelangelo (IT) | 2002-12-18 | — | — | EP | claimed |
| WO-2001062089-A1 | USE OF PIPERIDINE BENZODERIVATIVES AS FUNGICIDES | LEIS MICHELANGELO (IT) | 2001-08-30 | — | — | WO | claimed |