Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 8/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011648 | 0.83 | SLC6A4 (0.42) | ALDH1A1TDP1ITGB3ITGA2BITGAV | |
| SCHEMBL6011457 | 0.83 | ALDH1A1 (0.51) | ALDH1A1ITGB3ITGA2BITGAVCHRM2 | |
| Hydrochloric Acid SCHEMBL6011657 | 0.82 | SLC6A4 (0.41) | ALDH1A1TDP1ITGB3ITGA2BITGAV | |
| SCHEMBL8555011 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNACHRM1CHRM3KMT2A | |
| SCHEMBL6011372 | 0.81 | CHRM1 (0.44) | CA2ALDH1A1CHRM1CHRM3KMT2A | |
| Hydrochloric Acid SCHEMBL6011621 | 0.80 | CHRM1 (0.43) | CA2ALDH1A1TDP1SLC6A4CHRM1 | |
| SCHEMBL6469248 | 0.80 | CHRM1 (0.45) | CA2ALDH1A1SLC6A4CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL5119976 | 0.79 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6011410 | 0.79 | CHRM1 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL6011594 | 0.79 | CRBN (0.46) | CHRM1CHRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | HALE JEFFREY J (US) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094989-A1 | Pyrrolidine modulators of CCR5 chemokine receptor activity | CCR5, CCR1, CXCR1 | CA12 4856/4885CA1 4709/4885CA2 4520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.