Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606841 | 0.91 | NR1H3 (0.41) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL7611651 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7605332 | 0.85 | ABCB1 (0.37) | ALOX5KDM4EERN1 | |
| SCHEMBL7612302 | 0.82 | ALOX5 (0.45) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7764648 | 0.81 | KMT2A (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7611730 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7611589 | 0.80 | MAPT (0.44) | MAPTMEN1KMT2AALOX5 | |
| SCHEMBL7605446 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7607642 | 0.79 | NPC1 (0.47) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7606836 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |