Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610980 | 0.89 | MEN1 (0.44) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7611484 | 0.88 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7764640 | 0.86 | LPAR1 (0.41) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6985420 | 0.86 | PPARG (0.48) | KMT2AMEN1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL7769464 | 0.86 | CASR (0.46) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7768607 | 0.84 | SMN1; SMN2 (0.44) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7611651 | 0.82 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL7605451 | 0.81 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL6027885 | 0.81 | SMN1; SMN2 (0.46) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL7612302 | 0.78 | ALOX5 (0.45) | KMT2AMEN1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |