SCHEMBL7605547

SCHEMBL7605547

NC(=O)C(Cc1ccccc1)NC(=O)c1cccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F3 P13726 2/20 0.53
HPGDS O60760 5/20 0.52
KCNA5 P22460 1/20 0.51
MTTP P55157 8/20 0.51
APOB P04114 2/20 0.51
PPARG P37231 2/20 0.49
PPARD Q03181 2/20 0.49
PPARA Q07869 2/20 0.49
NR1H4 Q96RI1 2/20 0.49
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7605543 0.84 F3 (0.49) F3MTTPAPOB
SCHEMBL7605815 0.82 APOB (0.63) MTTPAPOBPPARGPPARDNR1H4
SCHEMBL7612180 0.82 MTTP (0.61) MTTPAPOBPPARGPPARDPPARA
SCHEMBL7605581 0.81 SENP1 (0.59) MTTPAPOBPPARGPPARDPPARA
SCHEMBL7615488 0.81 MTTP (0.63) MTTPAPOB
SCHEMBL7606402 0.81 MTTP (0.57) MTTPAPOBPPARGHTT
SCHEMBL7609363 0.81 MTTP (0.57) MTTPAPOBPPARGHTT
SCHEMBL7605756 0.81 APOB (0.57) MTTPAPOBPPARGPPARDPPARA
SCHEMBL6799012 0.80 APOB (0.66) MTTPAPOBPPARGPPARDPPARA
Hydrochloric Acid SCHEMBL7607266 0.80 APOB (0.65) MTTPAPOBPPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments MTTP, CETP, FABP1 F3 578/4885HPGDS 1298/4885KCNA5 3428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.