Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 5/20 | 0.66 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.63 |
| ▸ | PPARG | P37231 | 2/20 | 0.63 |
| ▸ | PPARD | Q03181 | 2/20 | 0.63 |
| ▸ | PPARA | Q07869 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | MTTP | P55157 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.55 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7607266 | 0.99 | APOB (0.65) | APOBNR1H4PPARGPPARDPPARA | |
| SCHEMBL7605815 | 0.93 | APOB (0.63) | APOBNR1H4PPARGPPARDRXFP1 | |
| SCHEMBL7607259 | 0.89 | APOB (0.59) | APOBNR1H4PPARGPPARDRXFP1 | |
| SCHEMBL7613563 | 0.89 | APOB (0.59) | APOBNR1H4PPARGPPARDPPARA | |
| SCHEMBL31393757 | 0.87 | CHRNB2 (0.71) | APOBHTTMTTPALDH1A1CHRNB2 | |
| SCHEMBL7048961 | 0.87 | CHRNB2 (0.71) | NR1H4HTTALDH1A1L3MBTL1CHRNB2 | |
| SCHEMBL3726223 | 0.86 | NPC1 (0.61) | APOBMTTPALDH1A1CHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL7611573 | 0.86 | CHRNB2 (0.69) | NR1H4HTTALDH1A1L3MBTL1CHRNB2 | |
| SCHEMBL7612180 | 0.86 | MTTP (0.61) | APOBNR1H4PPARGPPARDPPARA | |
| SCHEMBL7607240 | 0.86 | APOB (0.61) | APOBNR1H4PPARGPPARDRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| EP-1301464-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
| WO-2002004403-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | APOB 45/4885NR1H4 99/4885PPARG 86/4885 |
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | APOB 1/4885NR1H4 245/4885PPARG 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.