SCHEMBL7605543

SCHEMBL7605543

CCOC(=O)CC(NC(=O)c1cccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c1)C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F3 P13726 3/20 0.49
MTTP P55157 14/20 0.47
APOB P04114 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7610756 0.84 APOB (0.51) MTTPAPOBL3MBTL1
SCHEMBL7605547 0.84 F3 (0.53) F3MTTPAPOB
SCHEMBL7610500 0.82 APOB (0.51) MTTPAPOBL3MBTL1
SCHEMBL7605535 0.81 L3MBTL1 (0.51) MTTPAPOBL3MBTL1
SCHEMBL7605815 0.77 APOB (0.63) MTTPAPOBL3MBTL1
SCHEMBL7609278 0.77 ALDH1A1 (0.58) MTTPAPOB
SCHEMBL7608643 0.75 APOB (0.55) F3MTTPAPOBL3MBTL1
SCHEMBL6799012 0.75 APOB (0.66) MTTPAPOBL3MBTL1
SCHEMBL7612153 0.75 MTTP (0.54) MTTP
SCHEMBL7605511 0.75 APOB (0.56) MTTPAPOBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032238-A1 Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments MTTP, CETP, FABP1 F3 578/4885MTTP 1/4885APOB 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.