Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896286 | 0.85 | CES2 (0.48) | CES2CES1HSD11B1 | |
| SCHEMBL7896288 | 0.84 | CES1 (0.52) | CES2CES1HSD11B1RAB9A | |
| SCHEMBL7604796 | 0.74 | MAPT (0.47) | CES2CES1NPC1RAB9APLOD2 | |
| SCHEMBL7897615 | 0.73 | CES2 (0.45) | CES2CES1HSD11B1NPC1RAB9A | |
| SCHEMBL6945606 | 0.71 | HTR7 (0.44) | CES2CES1NPC1RAB9APLOD2 | |
| SCHEMBL16823 | 0.71 | CES1 (0.62) | CES2CES1NPC1RAB9APLOD2 | |
| SCHEMBL29035937 | 0.69 | CES1 (0.54) | CES2CES1NPC1RAB9APLOD2 | |
| SCHEMBL28356730 | 0.67 | CES1 (0.52) | CES2CES1NPC1RAB9APLOD2 | |
| SCHEMBL1272402 | 0.67 | CES1 (0.52) | CES2CES1NPC1RAB9APLOD2 | |
| SCHEMBL3441242 | 0.67 | CES1 (0.52) | CES2CES1NPC1RAB9APLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1026154-B1 | Preparation process of difluoroacetophenone derivatives | SSP CO LTD (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6229049-B1 | COUPLING AN ALKYLTHIODIFLUOROACETIC ACID ESTER DERIVATIVE TO A HALOBENZENE DERIVATIVE AS AN INTERMEDIATE FOR 'TRIAZOLES' FUNGICIDES; TREATING MYCOTIC INFECTIOUS DISEASES | SSP CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| US-6184396-B1 | 2-CYCLOPROPYLTHIADIFLUOROMETHYL-2-PHENYLOXIRANE INTERMEDIATES FOR 1-(CYCLOPROPYLTHIA)-2-PHENYL-1,1-(CYCLOPROPYLTHIA)-2-PHENYL-1,1-DIFLUORO-3-(1H-1,2,4-TRIAZOL-1-YL)-2-PROPANOL AND DERIVATIVES; FUNGICIDES; CANDIDA AND ASPERGILLUS | SSP CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| US-6172266-B1 | FUNGICIDES | SSP CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1026154-A2 | Preparation process of difluoroacetophenone derivatives | SSP Co., Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| US-6040325-A | FUNGICIDES FOR THE PREVENTION AND TREATMENT OF MAMMALIAN MYCOTIC INFECTIONS | SSP CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0933368-A1 | Triazole derivative or salt thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient (antimycotic) | SSP Co., Ltd. (JP) | 1999-08-04 | — | — | EP | disclosed |