Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605938 | 0.85 | CES2 (0.41) | CES2CES1HSD11B1 | |
| SCHEMBL7896288 | 0.83 | CES1 (0.52) | CES2CES1HSD11B1GAATSHR | |
| SCHEMBL7609999 | 0.75 | CES2 (0.55) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL7896290 | 0.74 | CES2 (0.53) | CES2CES1SRD5A2HSD11B1GAA | |
| SCHEMBL4023293 | 0.73 | HSD11B1 (0.63) | CES2CES1SRD5A2HSD11B1GAA | |
| SCHEMBL6942780 | 0.72 | CES2 (0.52) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL7886413 | 0.72 | PTPN1 (0.53) | CES2CES1SRD5A2HSD11B1GAA | |
| SCHEMBL23172558 | 0.72 | CES2 (0.67) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL1078685 | 0.72 | CES1 (0.67) | CES2CES1SRD5A2GSK3BPTPN1 | |
| SCHEMBL1855141 | 0.70 | HSD11B1 (0.60) | CES2CES1SRD5A2HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184396-B1 | 2-CYCLOPROPYLTHIADIFLUOROMETHYL-2-PHENYLOXIRANE INTERMEDIATES FOR 1-(CYCLOPROPYLTHIA)-2-PHENYL-1,1-(CYCLOPROPYLTHIA)-2-PHENYL-1,1-DIFLUORO-3-(1H-1,2,4-TRIAZOL-1-YL)-2-PROPANOL AND DERIVATIVES; FUNGICIDES; CANDIDA AND ASPERGILLUS | SSP CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| US-6172266-B1 | FUNGICIDES | SSP CO., LTD. (JP) | 2001-01-09 | — | — | US | disclosed |
| US-6040325-A | FUNGICIDES FOR THE PREVENTION AND TREATMENT OF MAMMALIAN MYCOTIC INFECTIONS | SSP CO., LTD. (JP) | 2000-03-21 | — | — | US | disclosed |
| EP-0933368-A1 | Triazole derivative or salt thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient (antimycotic) | SSP Co., Ltd. (JP) | 1999-08-04 | — | — | EP | disclosed |