Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945840 | 0.86 | RAB9A (0.70) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL28317903 | 0.81 | RAB9A (0.67) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7613161 | 0.81 | RAB9A (0.67) | NPC1RAB9AMEN1KMT2APTGS2 | |
| SCHEMBL7610748 | 0.80 | NPC1 (0.58) | NPC1RAB9AGAAPTGS2HDAC6 | |
| SCHEMBL1083061 | 0.76 | RAB9A (0.74) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL6035984 | 0.73 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL5584124 | 0.73 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL20695012 | 0.70 | RAB9A (0.60) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18229478 | 0.69 | NPC1 (0.70) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL3687614 | 0.69 | RAB9A (0.67) | NPC1RAB9AMAPTPTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082268-A1 | Therapeutic compounds for the treatment of asthma and allergy, and methods of use thereof | SEPRACOR INC. | 2002-06-27 | — | — | US | disclosed |
| WO-2001070737-A2 | THERAPEUTIC HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ASTHMA AND ALLERGY AND USE THEREOF | SEPRACOR, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082268-A1 | Therapeutic compounds for the treatment of asthma and allergy, and methods of use thereof | LTC4S, LTA4H, HRH2 | NPC1 2272/4885RAB9A 2823/4885MEN1 3193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.