Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 10/20 | 0.38 |
| ▸ | PTGES | O14684 | 7/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601816 | 0.94 | KMT2A (0.43) | KMT2APGRPTGS2PTGES | |
| SCHEMBL1080024 | 0.88 | PTGS2 (0.38) | PTGS2PTGES | |
| SCHEMBL7605922 | 0.85 | KMT2A (0.42) | KMT2APGRPTGS2PTGESHRH3 | |
| SCHEMBL7606107 | 0.83 | KMT2A (0.44) | KMT2APGRPTGS2PTGES | |
| SCHEMBL1081286 | 0.82 | PTGES (0.39) | PTGS2PTGES | |
| SCHEMBL7604012 | 0.81 | PGR (0.42) | KMT2APGRPDE4APDE4BPDE4C | |
| SCHEMBL7601260 | 0.80 | PGR (0.41) | KMT2APGRPTGESPDE4APDE4B | |
| SCHEMBL13660757 | 0.78 | PTGS2 (0.48) | KMT2APTGS2PTGES | |
| SCHEMBL1081288 | 0.78 | PTGES (0.38) | PTGS2PTGES | |
| SCHEMBL7601944 | 0.76 | KMT2A (0.42) | KMT2APGRPTGS2PTGESHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |