Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.48 |
| ▸ | PTGES | O14684 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692756 | 0.88 | PTGS2 (0.47) | PTGS2PTGES | |
| SCHEMBL1177769 | 0.82 | PTGS2 (0.46) | PTGS2PTGES | |
| SCHEMBL3698257 | 0.81 | PTGS2 (0.46) | PTGS2PTGES | |
| SCHEMBL7605922 | 0.79 | KMT2A (0.42) | PTGS2PTGESKMT2A | |
| SCHEMBL7601816 | 0.79 | KMT2A (0.43) | PTGS2PTGESKMT2A | |
| SCHEMBL7606107 | 0.78 | KMT2A (0.44) | PTGS2PTGESKMT2A | |
| SCHEMBL7601944 | 0.78 | KMT2A (0.42) | PTGS2PTGESKMT2A | |
| SCHEMBL7606070 | 0.78 | KMT2A (0.41) | PTGS2PTGESKMT2A | |
| SCHEMBL7601830 | 0.77 | PTGES (0.46) | PTGS2PTGESKMT2A | |
| SCHEMBL7909420 | 0.77 | KMT2A (0.45) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127338-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |