Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.34 |
| ▸ | HRH2 | P25021 | 12/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612299 | 0.82 | TACR1 (0.35) | TACR1 | |
| SCHEMBL7609141 | 0.81 | HRH2 (0.49) | HRH1HRH2HRH3ALDH1A1 | |
| SCHEMBL7606236 | 0.79 | MEN1 (0.48) | HRH1HRH2TACR1ALDH1A1CYP2C19 | |
| SCHEMBL4710700 | 0.73 | L3MBTL1 (0.53) | TACR1HRH3ALDH1A1CYP1A2 | |
| SCHEMBL4709553 | 0.72 | L3MBTL1 (0.57) | HRH3ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL20325180 | 0.72 | PAOX (0.44) | TACR1HRH3ALDH1A1 | |
| SCHEMBL7604063 | 0.71 | TACR1 (0.40) | HRH1HRH2TACR1 | |
| SCHEMBL21421662 | 0.71 | PAOX (0.46) | HRH1HRH2HRH3ALDH1A1 | |
| SCHEMBL26384682 | 0.71 | PAOX (0.46) | TACR1HRH3ALDH1A1 | |
| SCHEMBL27379980 | 0.70 | HRH1 (0.46) | HRH1HRH2HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927173-B1 | SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL | UCB SA (BE) | 2002-06-12 | — | — | EP | claimed |