SCHEMBL7606337

SCHEMBL7606337

Cc1cc(C(F)C(F)(F)C(F)(F)F)cc(C)c1Cl

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.37
CHRM1 P11229 1/20 0.37
ALOX15 P16050 1/20 0.37
MAOA P21397 1/20 0.37
TBXA2R P21731 1/20 0.37
ADRA1A P35348 1/20 0.37
HTR2B P41595 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043796 0.80 CA1 (0.39)
SCHEMBL7461092 0.80
SCHEMBL7602704 0.79 S1PR1 (0.35)
SCHEMBL4004119 0.76 LMNA (0.32)
SCHEMBL7784834 0.76
SCHEMBL28454384 0.72 ESR1 (0.41) CYP3A4ALOX15
SCHEMBL7458357 0.72 CHRNA1 (0.33)
SCHEMBL6666750 0.72 CYP3A4 (0.41) CYP3A4ALOX15
SCHEMBL28429152 0.71 SHBG (0.45)
SCHEMBL7606344 0.69 CYP3A4 (0.38) CYP3A4CHRM1ALOX15MAOATBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020064953-A1 Chemical mechanical polishing stopper film, process for producing the same, and method of chemical mechanical polishing JSR CORPORATION (JP) 2002-05-30 US disclosed