Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259598 | 0.86 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL7255219 | 0.84 | HPGD (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL7254788 | 0.82 | ALDH1A1 (0.60) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL7254930 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL7255908 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL7254970 | 0.80 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL9147815 | 0.80 | KMT2A (0.48) | ALDH1A1HPGDKMT2AMAPTRAB9A | |
| SCHEMBL7708496 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL6231503 | 0.79 | MAPK1 (0.54) | ALDH1A1CYP1A2CYP3A4CYP2C19MAPK1 | |
| SCHEMBL9146883 | 0.78 | TAS1R3 (0.49) | ALDH1A1HPGDKMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482962-B2 | CONTACTING HELMINTH, NEMATODE, INSECT OR ACARID PESTS OR PARASITES OR THEIR FOOD SUPPLY, HABITAT OR BREEDING GROUNDS WITH A NITROETHYL DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | claimed |
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | AMERICAN CYANAMID COMPANY | 2002-08-01 | — | — | US | claimed |
| US-6358883-B1 | FOR CONTROLLING NEMATODE, INSECT AND ACARID PESTS | AMERICAN CYANAMID COMPANY | 2002-03-19 | — | — | US | claimed |
| EP-1000934-A2 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | American Cyanamid Company (US) | 2000-05-17 | — | — | EP | claimed |
| US-6482962-B2 | CONTACTING HELMINTH, NEMATODE, INSECT OR ACARID PESTS OR PARASITES OR THEIR FOOD SUPPLY, HABITAT OR BREEDING GROUNDS WITH A NITROETHYL DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | disclosed |
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | AMERICAN CYANAMID COMPANY | 2002-08-01 | — | — | US | disclosed |
| US-6358883-B1 | FOR CONTROLLING NEMATODE, INSECT AND ACARID PESTS | AMERICAN CYANAMID COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1000934-A2 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | American Cyanamid Company (US) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103256-A1 | Pesticidal and parasiticidal use of 1-aryl-1-(substituted thio, sulfinyl and sulfonyl)-2-nitroethane compounds | SULT1E1, SULT1A1, TST | ALDH1A1 235/4885CYP1A2 37/4885CYP3A4 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.