Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | EPOR | P19235 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606168 | 0.91 | PTPN2 (0.41) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7606604 | 0.85 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7610616 | 0.85 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7605019 | 0.83 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7605883 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7610096 | 0.82 | HDAC3 (0.44) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7606579 | 0.82 | NR1H3 (0.43) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL7614716 | 0.80 | ALOX5 (0.39) | EPOR | |
| SCHEMBL7608457 | 0.79 | BCHE (0.41) | MAPTLMNARAB9ASMN1; SMN2EPOR | |
| SCHEMBL7609855 | 0.78 | NPC1 (0.44) | MEN1KMT2ANPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |