Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606163 | 0.91 | NR1H3 (0.47) | NR1H3MEN1KMT2ANPC1POLB | |
| SCHEMBL3978402 | 0.88 | ADRA1D (0.45) | MEN1KMT2AADRA1DADRA1AADRA1B | |
| SCHEMBL7605952 | 0.87 | NR1H3 (0.48) | NR1H3MEN1KMT2ANPC1POLB | |
| SCHEMBL7610361 | 0.87 | NR1H3 (0.46) | NR1H3MEN1KMT2ANPC1POLB | |
| SCHEMBL7611102 | 0.87 | NR1H3 (0.46) | NR1H3MEN1KMT2ANPC1POLB | |
| SCHEMBL11246930 | 0.86 | NR1H3 (0.51) | NR1H3MEN1KMT2AALDH1A1ABCB1 | |
| SCHEMBL7611188 | 0.84 | ALDH1A1 (0.46) | NR1H3MEN1KMT2ANPC1POLB | |
| SCHEMBL11597558 | 0.83 | ADRA1D (0.54) | NR1H3MEN1KMT2AADRA1DADRA1A | |
| SCHEMBL7605883 | 0.83 | ALDH1A1 (0.45) | NR1H3MEN1KMT2ANPC1POLB | |
| SCHEMBL7606579 | 0.83 | NR1H3 (0.43) | NR1H3MEN1KMT2ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |