Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSH | P09668 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610590 | 0.92 | CETP (0.43) | CETPPOLBTSHR | |
| SCHEMBL7609596 | 0.83 | LAP3 (0.44) | CETPALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7605254 | 0.77 | ACP3 (0.41) | CETPTSHR | |
| SCHEMBL27519157 | 0.77 | CETP (0.42) | CETPALDH1A1 | |
| SCHEMBL18859028 | 0.77 | ALDH1A1 (0.54) | CETPCNR2ALDH1A1CYP3A4CA2 | |
| SCHEMBL20841222 | 0.77 | ALDH1A1 (0.54) | CETPCNR2ALDH1A1CYP3A4CA2 | |
| SCHEMBL17625334 | 0.77 | ALDH1A1 (0.54) | CETPCNR2ALDH1A1CYP3A4CA2 | |
| SCHEMBL5051247 | 0.77 | PTGES (0.49) | CETPCNR2 | |
| SCHEMBL11488640 | 0.75 | CETP (0.47) | CETPCNR2CTSKCTSLCTSB | |
| SCHEMBL7607704 | 0.74 | MME (0.44) | CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515040-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | claimed |