Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417324 | 0.82 | LMNA (0.46) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL1844219 | 0.79 | AR (0.46) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL12438310 | 0.76 | LMNA (0.41) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL6825077 | 0.75 | AR (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL31493404 | 0.75 | KMT2A (0.48) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL7613860 | 0.74 | TP53 (0.38) | TP53ALDH1A1KMT2A | |
| SCHEMBL5121029 | 0.74 | RAB9A (0.49) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL1594682 | 0.74 | LMNA (0.45) | LMNAPTGER4CYP1A2CYP3A4MAOA | |
| SCHEMBL5115630 | 0.74 | SMN1; SMN2 (0.52) | LMNAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28343429 | 0.74 | CNR2 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198254-A1 | Polyamide analogs | GENELABS TECHNOLOGIES, INC. | 2002-12-26 | — | — | US | disclosed |
| WO-2002062755-A2 | POLYAMIDE ANALOGS AS DNA MINOR GROOVE BINDERS | GENELABS TECHNOLOGIES, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198254-A1 | Polyamide analogs | CYP51A1, HDAC6, ERG28 | LMNA 1778/4885PTGER4 4059/4885CYP1A2 1234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.