Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171804 | 0.89 | MAPT (0.62) | HTR7MAPTNPSR1PKMADRB1 | |
| SCHEMBL7610501 | 0.87 | HTR7 (0.60) | HTR7MAPTNPSR1PKMNPC1 | |
| Fluoride SCHEMBL27569822 | 0.87 | MEN1 (0.56) | HTR7MAPTNPSR1ADRB1SMN1; SMN2 | |
| SCHEMBL7105773 | 0.84 | ADRB1 (0.70) | MAPTNPSR1ADRB1NPC1RAB9A | |
| SCHEMBL10063748 | 0.84 | ADRB1 (0.70) | MAPTNPSR1ADRB1NPC1RAB9A | |
| SCHEMBL3414344 | 0.84 | ADRB1 (0.70) | MAPTNPSR1ADRB1NPC1RAB9A | |
| SCHEMBL30108226 | 0.83 | MELK (0.60) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6561470 | 0.80 | CHKA (0.59) | MAPTNPSR1PKMNPC1RAB9A | |
| SCHEMBL12418021 | 0.79 | MEN1 (0.50) | HTR7SMN1; SMN2TP53MEN1KMT2A | |
| Tannin Pyrogallol SCHEMBL1419994 | 0.79 | ACHE (0.62) | MAPTNPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210340-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES, THE PRODUCTION THEREOF AND THEIR UTILIZATION AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001014355-A1 | SUBSTITUTED PIPERAZINE DERIVATIVES, THE PRODUCTION THEREOF AND THEIR UTILIZATION AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-01 | — | — | WO | disclosed |