Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401047 | 0.86 | CA2 (0.49) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL7603661 | 0.83 | GPR35 (0.42) | GPR35NPSR1PDK1PDK2PDK3 | |
| SCHEMBL8751735 | 0.77 | GPR35 (0.42) | GPR35NPSR1ALDH1A1HTTMAOB | |
| SCHEMBL10400934 | 0.76 | LMNA (0.45) | CA2CA1ALDH1A1MAOBKDM4E | |
| SCHEMBL10880694 | 0.75 | CA2 (0.44) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL10400916 | 0.74 | RAB9A (0.47) | CA2CA1ALDH1A1HTTKDM4E | |
| SCHEMBL10400339 | 0.74 | CA1 (0.43) | CA2CA1NPSR1ACHE | |
| SCHEMBL13883939 | 0.74 | MAOB (0.51) | CA2MMP1MMP2MMP9MMP8 | |
| SCHEMBL16924652 | 0.74 | GPR35 (0.39) | GPR35NPSR1ALDH1A1HTTMAOB | |
| SCHEMBL10400823 | 0.73 | CA1 (0.42) | CA2CA1ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492075-B1 | COATING WITH CLEAVING COMPOUND TO CONTROLLABLY DECREASE SIZE OF DEVELOPED RESIST | ADVANCED MICRO DEVICES, INC. | 2002-12-10 | — | — | US | disclosed |
| US-6274289-B1 | Chemical resist thickness reduction process | ADVANCED MICRO DEVICES, INC. | 2001-08-14 | — | — | US | disclosed |