Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 17/20 | 0.68 |
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 8/20 | 0.59 |
| ▸ | DRD5 | P21918 | 3/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805479 | 0.90 | HTR7 (0.72) | HTR7DRD2HTR1ADRD5DRD3 | |
| SCHEMBL9044824 | 0.86 | HTR7 (0.66) | HTR7DRD2DRD4HTR1ADRD5 | |
| SCHEMBL31033189 | 0.86 | DRD2 (0.64) | HTR7DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL6923578 | 0.86 | CA1 (0.55) | HTR7DRD2DRD4HTR1ADRD5 | |
| SCHEMBL31033213 | 0.85 | DRD2 (0.56) | HTR7DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL2674982 | 0.84 | DRD2 (0.66) | HTR7DRD2DRD4DRD3 | |
| SCHEMBL9096389 | 0.82 | DRD2 (0.83) | HTR7DRD2DRD4HTR1ADRD5 | |
| SCHEMBL31033145 | 0.82 | ALDH1A1 (0.51) | HTR7DRD2DRD4HTR1ADRD5 | |
| SCHEMBL31033190 | 0.82 | ALDH1A1 (0.51) | HTR7DRD2DRD4HTR1ADRD5 | |
| SCHEMBL31033176 | 0.82 | ALDH1A1 (0.51) | HTR7DRD2DRD4HTR1ADRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685463-B1 | INDOLIN-2-ONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-05-22 | — | — | EP | claimed |