Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483548 | 0.85 | CASR (0.38) | ALDH1A1LMNACYP2C19TDP1TRPA1 | |
| SCHEMBL7607986 | 0.79 | CRHR1 (0.36) | KMT2APOLBALDH1A1LMNATDP1 | |
| SCHEMBL9227886 | 0.77 | PDE5A (0.33) | POLBALDH1A1 | |
| SCHEMBL7614292 | 0.77 | ESR1 (0.42) | LMNACYP2C19CHRM1SLC6A2ADRA1A | |
| SCHEMBL27391010 | 0.76 | TSHR (0.42) | KMT2APOLBALDH1A1LMNATDP1 | |
| SCHEMBL9226407 | 0.76 | POLB (0.39) | KMT2APOLBALDH1A1LMNATDP1 | |
| SCHEMBL9092834 | 0.74 | LMNA (0.36) | KMT2APOLBALDH1A1LMNACYP2C19 | |
| Hydrogen Peroxide SCHEMBL11334308 | 0.73 | TSHR (0.44) | KMT2APOLBALDH1A1LMNACYP2C19 | |
| SCHEMBL5494536 | 0.72 | ACHE (0.44) | ALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL5488498 | 0.72 | LMNA (0.35) | KMT2APOLBALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |